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Irene Paterniti Selected Research

(4- (((2- (3- fluoro- 4- (trifluoromethyl)phenyl)- 4- methyl- 1,3- thiazol- 5- yl)methyl)sulfanyl)- 2- methylphenoxy)acetic acid

7/2012Peroxisome proliferator-activated receptor β/δ agonist GW0742 ameliorates cerulein- and taurocholate-induced acute pancreatitis in mice.
1/2011Emerging role of PPAR-β/δ in inflammatory process associated to experimental periodontitis.
8/2010GW0742, a selective PPAR-beta/delta agonist, contributes to the resolution of inflammation after gut ischemia/reperfusion injury.
5/2010Evidence for the role of peroxisome proliferator-activated receptor-beta/delta in the development of spinal cord injury.
4/2010GW0742, a high-affinity PPAR -beta/delta agonist, inhibits acute lung injury in mice.
2/2010Role of PPAR-delta in the development of zymosan-induced multiple organ failure: an experiment mice study.

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Irene Paterniti Research Topics

Disease

56Inflammation (Inflammations)
05/2022 - 08/2009
29Spinal Cord Injuries (Spinal Cord Injury)
11/2020 - 05/2009
18Neuroinflammatory Diseases
07/2022 - 01/2011
13Ischemia
11/2021 - 02/2010
11Myelitis
01/2014 - 05/2009
10Reperfusion Injury
11/2021 - 02/2010
9Wounds and Injuries (Trauma)
01/2021 - 02/2011
8Neurodegenerative Diseases (Neurodegenerative Disease)
07/2022 - 01/2014
8Neoplasms (Cancer)
02/2022 - 02/2018
7Traumatic Brain Injuries (Traumatic Brain Injury)
01/2021 - 12/2014
6Parkinson Disease (Parkinson's Disease)
07/2022 - 01/2012
6Pleurisy (Pleuritis)
05/2014 - 02/2010
5Edema (Dropsy)
11/2020 - 11/2010
5Aneurysm (Aneurysms)
01/2019 - 08/2011
5Shock
07/2011 - 02/2010
4Glioblastoma (Glioblastoma Multiforme)
10/2022 - 12/2020
4Psoriasis (Pustulosis Palmaris et Plantaris)
03/2022 - 04/2016
4Body Weight (Weight, Body)
05/2012 - 02/2010
4Pneumonia (Pneumonitis)
10/2011 - 02/2010
4Multiple Organ Failure (MODS)
07/2011 - 02/2010
4Septic Shock (Toxic Shock Syndrome)
07/2011 - 02/2010
3Migraine Disorders (Migraine)
04/2022 - 02/2020
3Mouth Neoplasms (Oral Cancer)
12/2021 - 07/2021
3Hyperalgesia
02/2020 - 11/2010
3Colitis
04/2016 - 01/2010
3Necrosis
04/2016 - 10/2011
3Brain Ischemia (Cerebral Ischemia)
01/2016 - 02/2011
3Lung Injury
05/2014 - 07/2011
3Spinal Cord Compression
07/2013 - 04/2011
3Brain Injuries (Brain Injury)
04/2013 - 02/2011
3Pancreatitis
07/2012 - 05/2012
3Periodontitis
01/2011 - 01/2010
2Alzheimer Disease (Alzheimer's Disease)
07/2022 - 01/2014
2Squamous Cell Carcinoma of Head and Neck
12/2021 - 10/2021
2Acute Lung Injury
08/2021 - 04/2010

Drug/Important Bio-Agent (IBA)

21CytokinesIBA
03/2022 - 05/2009
12palmidrolIBA
05/2016 - 08/2011
113-nitrotyrosineIBA
01/2014 - 05/2009
10Peroxisome Proliferator-Activated Receptors (PPAR)IBA
10/2022 - 05/2009
10Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
10/2020 - 05/2009
9CarrageenanIBA
04/2020 - 02/2010
7LuteolinIBA
10/2020 - 07/2013
7Peroxidase (Myeloperoxidase)IBA
01/2018 - 01/2010
7Neuroprotective AgentsIBA
01/2018 - 02/2011
6LigandsIBA
10/2022 - 02/2010
6Proteins (Proteins, Gene)FDA Link
07/2022 - 05/2010
6AntioxidantsIBA
06/2022 - 07/2013
6(4- (((2- (3- fluoro- 4- (trifluoromethyl)phenyl)- 4- methyl- 1,3- thiazol- 5- yl)methyl)sulfanyl)- 2- methylphenoxy)acetic acidIBA
07/2012 - 02/2010
6NF-kappa B (NF-kB)IBA
07/2012 - 05/2009
5Prolyl OligopeptidasesIBA
11/2021 - 12/2020
5EnzymesIBA
01/2021 - 01/2010
5Pharmaceutical PreparationsIBA
01/2021 - 01/2011
5LipopolysaccharidesIBA
01/2021 - 08/2017
5FumaratesIBA
07/2020 - 04/2016
5Dimethyl FumarateIBA
07/2020 - 04/2016
5Glial Fibrillary Acidic ProteinIBA
01/2018 - 04/2013
5co-ultraPEALutIBA
01/2016 - 07/2013
5Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
12/2014 - 02/2010
4MelatoninIBA
03/2022 - 08/2009
44-phenylbutanoyl-prolylcyanopyrrolidineIBA
12/2021 - 07/2021
4Nerve Growth Factors (Neurotrophins)IBA
04/2021 - 04/2011
4Cyclooxygenase 2 (Cyclooxygenase-2)IBA
10/2020 - 11/2010
4Transcription Factors (Transcription Factor)IBA
01/2019 - 05/2009
4Liver X ReceptorsIBA
01/2017 - 02/2010
4olprinoneIBA
10/2011 - 07/2010
4NADPH Oxidases (NAD(P)H oxidase)IBA
07/2011 - 02/2011
4ZymosanIBA
07/2011 - 02/2010
4acetovanillone (apocynin)IBA
03/2011 - 11/2010
4PPAR-betaIBA
08/2010 - 02/2010
3InflammasomesIBA
10/2021 - 01/2019
3xyloglucanIBA
09/2021 - 01/2020
3Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
11/2020 - 01/2010
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2018 - 02/2010
3Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2017 - 11/2010
3DinitrobenzenesIBA
04/2016 - 01/2010
3Fatty Acids (Saturated Fatty Acids)IBA
08/2015 - 05/2009
3CeruletideIBA
07/2012 - 05/2012
3oleuropein aglyconeIBA
05/2012 - 08/2011
3Olive OilIBA
05/2012 - 08/2011
32- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA
05/2012 - 02/2010
3Mitogen-Activated Protein KinasesIBA
05/2012 - 02/2011
3GlucocorticoidsIBA
01/2012 - 05/2009
3Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
10/2011 - 05/2010
3Poly Adenosine Diphosphate RiboseIBA
07/2011 - 02/2010
3Tyrosine (L-Tyrosine)FDA Link
11/2010 - 01/2010
3T0901317IBA
02/2010 - 02/2010
2Therapeutic UsesIBA
10/2022 - 07/2020
2diazonaphthalenedisulfonic acid (NDS)IBA
06/2022 - 07/2020
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
05/2022 - 01/2012
2Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
05/2022 - 12/2020
2Butyric Acid (Butanoic Acid)IBA
04/2022 - 10/2021
2Volatile Fatty AcidsIBA
04/2022 - 10/2021
2sodium propionateIBA
04/2022 - 10/2021
2MicroRNAs (MicroRNA)IBA
02/2022 - 04/2021
2Biological ProductsIBA
02/2022 - 01/2016
23- (4- methylphenylsulfonyl)- 2- propenenitrileIBA
10/2021 - 11/2020

Therapy/Procedure

14Laminectomy
01/2019 - 05/2009
11Therapeutics
04/2022 - 02/2010
5Surgical Instruments (Clip)
01/2019 - 08/2011
3Drug Therapy (Chemotherapy)
04/2021 - 01/2015